Alzheimer’s Disease and Mercury – the Evidence

Alzheimer’s disease is a truly horrific condition that affects nearly 6 million Americans and is estimated to triple in prevalence during the next thirty years. And, despite the fact that the National Institute of дженерик сиалис купить (NIH) spends billions of dollars per year researching it, we’re often told either that the cause is still unknown or that it’s actually the result of faulty genes.

But is this true? Are we really still that far from understanding what causes this cruelest of diseases, and thus totally in the dark about how to stop it? Unfortunately, most people don’t know the reality of the situation, namely that there has been substantial research demonstrating the exact biochemical mechanisms by which mercury induces Alzheimer’s disease.

Despite the predominant attitude in the mainstream that Alzheimer’s is definitively not related to heavy metals, there is massive, detailed evidence that confidently establishes a link between the two. It all goes back to the story of Dr. Boyd Haley and the startling information he uncovered in his lab. Boyd Haley, PhD is a professor of biochemistry who has done perhaps more work than anyone on establishing the biological plausibility of mercury causing Alzheimer’s disease.

Decades ago, Dr. Haley researched the biochemical differences between the brains of normal people and those with Alzheimer’s using a technique he pioneered that enabled him to look closely at the activity of various enzymes in living tissue. His team found that certain enzymes were inhibited in Alzheimer’s patients by 80 or even 99 percent in some cases, in comparison with controls. He was then given a grant to study these enzyme differences for five years in an attempt to determine what could be affecting them.

After reviewing some of the existing literature demonstrating that Alzheimer’s patients tend to have more mercury in their brains than average people, Dr. Haley began to look at the effects of mercury on these enzymes and how it might lead to some of the hallmark neurological changes associated with this crippling disease.

NFTs, or Neurofibrillary Tangles, are what occur when tau proteins malfunction. Ordinarily, tau proteins assist the internal support structures of the neurons, called microtubules, giving them structural integrity. In patients with Alzheimer’s, these proteins become dysfunctional and accumulate abnormally, creating NFTs, which impair the function of the brain by interfering with the synaptic connections between neurons.

Based on Dr. Haley’s analysis of the biochemistry of mercury, it should chemically interfere with the brain’s production of tubulin, a protein needed in the creation of microtubules, and could therefore cause NFTs. In order to prove this concept in the laboratory, he exposed rats to mercury vapor and found that, as predicted, their brains began to form NFTs identical to those found in Alzheimer’s patients.

Glutamate is a powerfully excitatory neurotransmitter that has been linked to depression, schizophrenia, and suicide. In all these cases, there is an excessive amount present in the brain. Interestingly, glutamate levels are also elevated in patients with Alzheimer’s. Whenever there is too much of an excitatory neurotransmitter (one that leads to increased firing of neurons), the result can be excitotoxicity. This is also the same mechanism whereby aspartame has been accused of causing brain damage. Dr. Haley used his knowledge of biochemistry to then look at glutamine synthetase, an enzyme whose function is to break down glutamate, protecting the brain by preventing excessive levels of this overstimulating neurotransmitter.

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